Afatinib is used to treat a type of lung cancer (non-small cell lung cancer) that can spread to other organs in the body. Afatinib (Gilotrif) is a kinase inhibitor. The drug Afatinib works by slowing or stopping the growth of cancer cells. This drug binds to a protein (epidermal growth factor receptor – EGFR) in some tumors. Talking about Afatinib (Gilotrif) 40 mg Cost in South Africa, it is quite costly. Also, you cannot buy it randomly at any store.
Afatinib (Gilotrif) 40 mg tablet Cost in South Africa
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How should you take Afatinib?
Read the user manual carefully before use. If you have any questions, you should consult your doctor or pharmacist.
Take this medication by mouth as directed by your doctor, usually once a day, at least 1 hour before or 2 hours after a meal.
Dosage is based on your medical condition, response to treatment, and other medications you are taking. Be sure to tell your doctor and pharmacist about all the products you take (including prescription drugs, over-the-counter medicines, and supplements).
To achieve maximum effect, you should take the drug fully and regularly. You should take your medicine at the same time each day to make it easier to remember.
Do not increase your dose or take it more often or for longer than indicated. Your condition will not improve any faster, and your risk of serious side effects may increase.
Because the drug can be absorbed through the skin and lungs, and may be harmful to an unborn child, women who are pregnant or may become pregnant should not handle or breathe dust from the medicine. If you want to know exact Afatinib (Gilotrif) 40 mg Cost in South Africa so please contact us WhatsApp & Email Now.
How should Afatinib be stored?
Store at room temperature, protected from moisture and light. Do not store in the bathroom. Do not store in the freezer. Each drug may have different storage methods. Read the storage instructions on the package carefully, or ask your pharmacist. Keep medicine out of reach of children and pets.
Do not throw medication down the toilet or plumbing unless told to do so. Dispose of medication properly when it is past its expiration date or cannot be used. Consult your pharmacist or local waste disposal company about safe disposal of medications. If you want to know exact Afatinib (Gilotrif) 40 mg Cost in South Africa so please contact us WhatsApp & Email Now.
The information provided is not a substitute for medical professional advice. Always consult your doctor or pharmacist before deciding to take a medication.
What is the adult dose of Afatinib?
Usual Adult Dose for Non-Small Cell Lung Cancer:
Oral: 40 mg per day.
Duration of treatment: until the patient can no longer tolerate the drug or the disease progresses.
Note to take the medicine at least 1 hour before or 2 hours after a meal
What is the dose of Afatinib for children?
Dosage for children has not been studied and decided yet. Consult your doctor if you are giving this medicine to a child.
What forms and strengths does Afatinib have?
Afatinib has the form and strength of: tablets, oral: 20 mg, 30 mg, 40 mg. If you want to know exact Afatinib (Gilotrif) 40 mg Cost in South Africa so please contact us WhatsApp & Email Now.
What side effects will you experience when taking Afatinib?
All medicines can cause side effects, however, many people may not have or have only mild side effects. Consult your doctor if any of the following effects persist or worsen:
- Acne ;
- chapped lips;
- Dry skin;
- Mild itching;
- Runny nose ;
- Weight loss.
Contact your doctor right away if any of these serious side effects occur:
- serious allergic reactions (rash, hives, difficulty breathing, chest tightness, swelling of the mouth, face, lips or tongue);
- Blood in urine;
- Change in the amount of urine, fast or irregular heartbeat ;
- Lesions or sores in the mouth;
- Fingernail or toenail problems;
- severe or persistent diarrhea;
- Shortness of breath;
- Unusual , sudden weight loss ; swelling of the hands, arms, ankles, or legs;
- Difficulty urinating.
- Not everyone experiences these side effects. Other side effects not mentioned may occur. If you have any questions about side effects, consult your doctor or pharmacist.
What should you know before taking Afatinib?
Before taking Afatinib, you should pay attention to a few things:
Tell your doctor and pharmacist if you are allergic to Afatinib or any of its ingredients. Consult your pharmacist for a list of ingredients. If you want to know exact Afatinib (Gilotrif) 40 mg Cost in South Africa so please contact us WhatsApp & Email Now.
Tell your doctor and pharmacist if you are taking any prescription or over-the-counter medicines, herbs or supplements, especially:
- Amiodarone (Cordarone, Pacerone);
- certain antifungal medications such as itraconazole (Sporanox) and ketoconazole (Nizoral);
- Cyclosporine (Gengraf, Neoral, Sandimune);
- Erythromycin (EES, Erythrocin,...);
- some HIV medicines, such as nelfinavir (Viracept), ritonavir (Norvir, Kaletra), and saquinavir (Invirase);
- certain seizure medications, such as carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital , phenytoin (Dilantin);
- Quinidine (in Nuedexta);
- Rifampin (Rimactane, Rifadin, in Rifater);
- Tacrolimus (Prograf);
- Verapamil (Calan, Covera, Isoptin, Verelan).
There are many drugs that can interact with Afatinib that are not on the list, you should list all the medicines you are taking with your doctor, including those not on the list above. Your doctor may change the dose of your medicine or watch you carefully for signs of side effects. If you want to know exact Afatinib (Gilotrif) 40 mg Cost in South Africa so please contact us WhatsApp & Email Now.
Tell your doctor about any herbs you are taking, especially St. John's wort.
Tell your doctor if you are of Asian descent or have ever had lung or breathing problems (except lung cancer); eye problems , including dry eyes; heart problems; liver or kidney disease; or any other health condition. Also, tell your doctor if you are wearing contact lenses.
If you are pregnant or planning to become pregnant, or are breast-feeding. Breastfeeding is not recommended during treatment. Pregnancy should not be started while taking the drug, wait at least two weeks after treatment. Consult your doctor about appropriate methods of contraception. If you become pregnant while taking this medicine, tell your doctor. The drug can harm an unborn baby.
You need to avoid going out in the sun, if you have, you must cover it carefully. The drug Afatinib makes the skin sensitive to the sun and prone to acne and rashes during treatment.
Things to keep in mind if you are pregnant or breastfeeding
There are not enough studies to determine the risks of taking this medicine during pregnancy or breast-feeding. Before taking medication, always consult with your doctor to weigh the benefits and risks. If you want to know exact Afatinib (Gilotrif) 40 mg Cost in South Africa so please contact us WhatsApp & Email Now.
According to the US Food and Drug Administration (FDA), this drug belongs to the category D drug for pregnancy. You can refer to the table of drugs used for pregnant women below:
A= No risk;
B = No risk in some studies;
C = Possible risk;
D = There is evidence of risk;
X = Contraindications;
N = Don't know yet.
What drugs can Afatinib interact with?
Drug interactions can change how a drug works or increase the effect of side effects. This document does not cover all possible drug interactions. It's best to write down a list of all the medications you're taking (including prescription and over-the-counter medicines and supplements) to show your doctor or pharmacist. You should not take, stop or change the dose of the drug without your doctor's approval.
Many prescription and over-the-counter medications (eg, blood pressure medications, heart medications, HIV, weakened immune systems , infections, epilepsy), multivitamin products , herbs (eg. eg, St. John's wort) or diet because these drugs may interact with the drug Afatinib. Ask your doctor or pharmacist if you are not sure if a medicine you are taking could interact with Afatinib. If you want to know exact Afatinib (Gilotrif) 40 mg Cost in South Africa so please contact us WhatsApp & Email Now.
Can food and alcohol interact with afatinib?
Consult your health professional about taking your medicine with food, alcohol and tobacco.
What medical conditions affect afatinib?
Your medical condition may affect the use of this medicine. Tell your doctor if you have any health problems, especially:
- a history of eye problems (eg, keratitis, corneal ulcers , severe dry eyes );
- Heart disease;
- Kidney disease;
- Liver failure;
- History of lung disease (eg, interstitial lung disease, pneumonia): use with caution. May make these conditions worse.
What should you do in case of an emergency or overdose?
In the event of an emergency, call 911 immediately or go to the nearest local Health station. If you want to know exact Afatinib (Gilotrif) 40 mg Cost in South Africa so please contact us WhatsApp & Email Now.
Overdose symptoms may include:
What should you do if you miss a dose?
If you forget a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Note that double the prescribed dose should not be taken. If you want to know exact Price of Afatinib (Gilotrif) 40 mg in South Africa so please contact us WhatsApp & Email Now.
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